Best Supplements and Vitamins for Anti-Aging
I loved the movie The Wizard of Oz as a child. I think the message holds true and applies to our quest for anti-aging solutions.
The characters in The Wizard of Oz discover that the qualities they sought lay within them all along. Similarly, our strongest data regarding longevity rests on individual behavior centered around diet, exercise, sleep, and emotional connection.
Rather than looking toward supplements and vitamins for anti-aging, we should first explore more holistic means of improving our long-term health.
A Flooded Market
There’s a growing list of medications and supplements touted to prolong life. Experts expect the global anti-aging market to increase by 13% annually through 2030, meaning everyone who wants to make a buck on vitamins for anti-aging will have no problem doing so.
The media obsessively pursues “the next big thing” on the market, publishing all the clickbait they can to facilitate its success. All this hype leads to a lack of healthy skepticism regarding the data behind these new products (e.g., metformin, rapamycin, taurine, and resveratrol).
What’s the Problem?
The problem with these new interventions is the weak or nonexistent data supporting them.
Humans aren’t lab rats. Given the inherent duration needed for study (a lifetime) and its complexity, it’s almost impossible to perform a randomized controlled trial for most, if not all, of the anti-aging supplements on the market.
We’re not talking about a 12-week trial to test whether one’s cholesterol decreases. Testing to determine whether humans live longer is much more complicated and time-consuming.
Because we don’t have access to the gold standard of evidence — randomized controlled trials — we must extrapolate from inherently flawed experimental methods.
For example, many dietary supplements go through epidemiologic studies that aren’t randomized. They simply observe who eats or doesn’t eat and look for correlative outcomes.
One problem here is the presence of confounders. Another problem is that we’re forced to rely on animal models. Animals and humans differ in many ways, so results don’t always correlate.
Examples of Popular Products and Insufficient Studies
The following two examples are popular supplements hailed by the media as keys to longevity but which currently lack sufficient study and evidence.
Resveratrol
Resveratrol is a natural polyphenol found in red wine. Its study harbors a classic example of a confounder.
Many claim the resveratrol found in red wine is the answer to the “French paradox” (the generally low rates of heart disease observed in French people).
The flaw in this logic is something called a healthy user bias. This means the people consuming the wine are inherently different from those who don’t (i.e., higher socioeconomic status, greater consumption of fruits and vegetables, etc.). These variables likely have as great an impact on the user’s health as intake of resveratrol.
Furthermore, no current data supports the idea that resveratrol helps people (or animals) live longer.
Taurine
Taurine is an amino acid that our bodies produce. It has many functions, including as a neurotransmitter in the brain. While animal studies have shown links between taurine and longevity in worms and rodents, animal models aren’t always useful for human applications.
For example, the animal models supporting intermittent fasting were originally derived from mouse models. The conclusion: Eat all your meals within an eight-hour window and fast for 16 hours a day.
The caveat here is that a mouse will die after 48 hours without food. So, for a mouse, a 16-hour fast is one-third of the duration until death. That duration doesn’t correlate with the intermittent fasting we recommend. Humans can go an average of three weeks without food, so an equivalent fasting duration would be one week.
So, as Peter Attia puts it, taurine may be the “elixir of life if you’re a mouse,” but humans don’t manufacture, absorb, or excrete taurine the same way mice do. Therefore, the studies examining mice and taurine aren’t as useful as some would like to believe.
Today’s Takeaways
Given our imperfect data, our best anti-aging bet is to go back to the basics — risk versus reward.
Everything we recommend regarding nutrition, exercise, sleep, and social connections is the best we can offer. We know these measures improve longevity, and they’re 100% safe.
While the world tells you to “click here!” to order supplements or vitamins for anti-aging, remember there’s a man behind the curtain. The journey down the yellow brick road is more important than what lies at the end.
The Therapeutic Benefits of Nature
Whether I’m biking, jogging, or walking my dog, exercising in nature has always been my go-to stress reliever.
Some people prefer to exercise in the morning, checking it off the list to get it out of the way. I enjoy exercising at the end of the day to unwind from work.
This wasn’t always the case. In college, I’d go on long runs in the park before stressful tests. I remember one test in organic chemistry. I hadn’t timed my run properly and literally had to run to the lecture hall and take the test in my running gear.
I pitied the students who had to sit next to sweaty me, but I aced the test, did well as a premed, and the rest is history.
My personal experience has convinced me of the tremendous value of both exposure to nature and exercise. Is there any scientific data to validate the benefits of exposure to nature?
What Science Says About the Benefits of Nature
Delving into the literature around the therapeutic benefits of nature exposure reveals a large body of evidence associating nature exposure with a wide range of benefits. These benefits include stress reduction, better sleep, less depression, better cognitive function, lower blood pressure, better immune function, better post-op recovery, and more.
However, as we’ve mentioned in previous blog posts, correlation doesn’t equal causation. For example, access to parks correlates with higher socioeconomic status, and the decision to visit a park correlates with a higher level of physical function.
Very few gold-standard randomized controlled trials have successfully isolated the intervention of exposure to nature. However, I did find one notable study.
The Experiment
In 2018, a group of researchers from the University of Pennsylvania worked with a nonprofit to explore the therapeutic impact of “greening.” Greening is the process of cleaning up an urban property and planting live plants to “green up” the space.
This experiment used 110 clusters containing 541 vacant lots in areas of lower socioeconomic status in the city of Philadelphia. These lots were often blighted with graffiti, abandoned cars, and garbage.
The experimental methodology was this:
- One-third of the lots were cleaned up, planted as green space, and fenced off.
- One-third of the lots were cleaned up and fenced off but had no additional greening.
- One-third of the lots were left untouched (control group).
The researchers identified 442 participants in the neighborhoods adjacent to these areas and performed a mental health questionnaire before the intervention and again 18 months later.
The researchers documented that the participants adjacent to the green space versus the control spaces experienced a 41.5% reduction in depression and a 62.8% reduction in feelings of worthlessness.
This study gives plausibility to the mechanisms of all other association trials. Since strictly randomized controlled trials are so difficult in this case, the fact that this one demonstrated that nature exposure could be beneficial lends credence to other studies.
The full health benefits of nature walks, mountain biking, swimming, jogging, and anything else we enjoy doing outdoors may not be completely documented, but they’re worth investigating.
Is Data Necessary?
As we’ve said in recent posts, when in doubt, it’s often best to calculate risk versus reward.
If a situation involves significant risk, we need ironclad data from reproducible, randomized controlled trials showing a benefit to warrant the risk.
Take chemotherapy, for example. It involves tremendous risk to the patient, so we rely on the decades of study available to show us the benefits of the treatment to weigh whether the risk is worth it. The answer depends on each individual and their unique situation.
However, nature exposure is at the opposite end of this spectrum. There’s almost no risk for most people to spend time in nature, and the potential benefits are great. Because of this, we don’t need stacks of data from decades of gold-standard studies.
Today’s Takeaways
We’ve explored the potential risks and benefits of exposure to nature and green spaces. It’s safe to say the benefits far outweigh the risks for almost everyone. To offset even minimal risk, remember these tips:
- Always wear sunscreen — you can get sunburned even when it’s cloudy.
- Stay hydrated — drink plenty of water when it’s hot.
- Maintain situational awareness — watch your step if there are dogs around.
- Have fun and improve your health — find the best way for you to enjoy nature’s benefits.
Fall Vaccine Update 2023
Autumn, a time for changing seasons, beginning school, and thinking about vaccinations. This year there are three vaccines to discuss: influenza – the perennial classic, COVID – becoming a new tradition and Respiratory Syncytial Virus (RSV) – the new kid on the block.
RSV can cause mild cold symptoms such as coughing, fever, congestion, and sneezing. Symptoms can last for a week or two. Unfortunately, two groups of people are at risk for more serious outcomes. Children under five are more susceptible to bad outcomes with 60,000-80,000 hospitalizations and 100-300 deaths per year. Also, for those over 65 there are 60,000 – 150,000 hospitalizations and 6,000-10,000 deaths per year.
The Fall and Winter of 2022-2023 was one of the worst RSV seasons in recent memory due to many people coming out of COVID isolation and gathering with each other in larger numbers spreading the illness through society. The rate of hospitalizations for those over 65 shot up two-fold. Because there is no specific treatment for RSV in adults, other than supportive care, there is a great need for preventative treatment such as a vaccine.
In the Summer of 2023, CDC’s Advisory Committee on Immunization Practices (ACIP) met to evaluate two new RSV vaccine options: Abrysvo by Pfizer and Arexvy by GSK. Both have been approved for use in those over 60 years old and are currently available. Both pharmaceutical companies are in the midst of marketing campaigns for the vaccines. You may have, or will soon, see their advertisements.
For better or worse, practicing medicine during the COVID pandemic has led to diminished trust in our federal health agencies, creating healthy skepticism and a desire to more critically examine their decisions. At Banner Peak Health, we have reviewed some of the data submitted to the CDC for the two RSV vaccines and have come to our own conclusions.
Both vaccines underwent randomized controlled trials. Ideally, we would have wanted to see evidence of a reduction in hospitalizations and deaths due to RSV. Unfortunately, the two studies didn’t have enough participants to be able to document these critical outcomes. The studies only demonstrated a reduction in illness and symptoms not severe enough to lead to hospitalizations. Furthermore, several hundred people would need to receive the vaccine for every one episode of this level of illness avoided.
Most concerning for these vaccine side effects was their rate of two potentially fatal autoimmune central nervous system diseases, Guillain Barre Syndrome and Acute Disseminated Encephalomyelitis. These were very rare complications occurring in 1 out of 7,500 to 15,000 study participants. However, this rate is much higher than normal in the population and much higher than the rate observed in other vaccines such as influenza and Shingrix (shingles).
How to interpret this data?
These vaccines may be powerful tools for reducing hospitalizations and deaths from RSV, and their rate of dangerous autoimmune complications may have been overstated in these trials to due the randomness associated with the trials. Only a handful of cases occurred. However, the data submitted to the CDC does not support the pharmaceutical companies’ recommendation that everyone over the age of 60 receive the vaccine. The risk/benefit ratio based on the existing data is not strong enough. Basically, more studies and time for follow-up are needed to better understand the strengths and weaknesses of these vaccines.
Nonetheless, RSV is still a potentially lethal disease for those with high-risk health conditions. For these individuals, the protection from the vaccine outweighs the very small risk of a side effect.
In the meantime, our policy at Banner Peak Health:
- If you or a family member are at high-risk for a bad outcome from RSV, please get the vaccine. It is now available at local pharmacies. We define high risk as having a compromised immune system due to illness or medication, current cancer treatment, as well as a severe illness affecting your kidneys, heart, or lungs. If you are uncertain as to your status, please contact us to discuss the issue.
- Everyone else should wait. Hopefully, by next year, we will have more complete information to assess whether to use the vaccines.
Brief COVID Update:
The worst of the pandemic may be over, but COVID is still with us. We are in yet another surge, driven by the emergence of a new variant dubbed Eris- EG.5 (XBB1.9) which currently makes up around 15% of reported cases. Eris can be thought of as the grandchild of Omicron; it’s still highly contagious, but not causing as severe a disease as some of the original variants which have vanished from the human population. So far, Eris symptoms are like previous Omicron variants, possibly with less loss of taste and smell than its grandfather Omicron.
A new vaccine targeting a more recent variant, Omicron XBB.1.1.5, should be available in late September or early October. Raising the question, get the existing bivalent COVID booster now or wait and get the newer version?
We recommend waiting for the newer vaccine which more closely targets the current variant and should be available in a few months. However, if you are planning on traveling or have a high-risk gathering planned, you will need protection sooner and would benefit from getting the current vaccine as soon as possible.
Influenza:
The theme of appropriate timing applies to influenza vaccination as well. We will have our influenza vaccines in early September. The high dose Fluzone vaccine is recommended for everyone over 65, and Flublok is for those under 65 or anyone with an egg allergy. We prefer Flublok over other quadrivalent vaccines because it is less allergenic (not grown in eggs) and more potent since it contains a higher amount of hemagglutinins than the standard quadrivalent flu vaccines offered in the pharmacy.
We recommend that you wait until October to receive your influenza vaccination. A slight delay ensures that the 3-4 months of peak protection will cover a bit later into the flu season which often peaks a bit later here in California. However, if you plan to travel in October, receiving the vaccine in September is okay to ensure adequate time to respond to the vaccine before traveling.
What about receiving more than one vaccine at a time? Not a good idea. Simultaneous vaccinations increase the side effect burden and can create uncertainty as to which vaccine you had a reaction to.
In Summary:
For RSV, unless you or a family member are high risk, please wait to receive the vaccine this season. We define high-risk as having a compromised immune system due to illness or medication, current cancer treatment, as well as a severe illness affecting your kidneys, heart, or lungs. If you are uncertain as to your status, please contact us to discuss the issue.
For COVID, please wait for the release of the new COVID vaccine due in late September or early October.
If you are planning to travel or have high-risk gatherings planned, and it’s been more than four months since your last booster or infection, please get a booster now.
For influenza, please wait until October to ensure that your maximum antibody levels will remain effective throughout the flu season. You can be vaccinated at a pharmacy, or we will have a series of flu vaccine clinics later in the Fall. It is okay to receive the flu vaccine in September if you plan to travel in October.
Please contact us with any questions.
How Does Garmin Measure Stress?
Garmin and other wearables that measure heart function quantify stress. But how does Garmin measure stress, exactly?
These devices use heart rate variability (HRV) to quantify stress levels. But is HRV an accurate way to measure stress? The short answer is yes, absolutely.
But now that we can measure our HRV and determine our stress levels with wearables like Garmin, what do we do about it?
That’s what we’ll cover in this post.
Your HRV Is Like a Tesla
I like cars. In 2019, I was fortunate enough to get a Tesla Model 3.
There aren’t many gauges on an electric vehicle’s dashboard, but there is a charge indicator that tells whether you’re consuming electricity (by accelerating onto the freeway or climbing a steep hill, for example) or recharging your battery. As humans, we have a comparable gauge — heart rate variability (HRV).
Let me explain.
Our autonomic nervous system controls all our essential, automatic biological functions. It comprises two almost opposing systems:
- The sympathetic nervous system, which mediates our fight-or-flight response, dilates our pupils for improved vision, enhances our oxygen capacity to run faster, and more. It primes body for action.
- The parasympathetic nervous system, or the “rest and digest” system, which helps with digestion and recovery.
Knowing where we are on the spectrum between the two competing forces of our autonomic nervous system is vital to our health. The key to understanding that balance is heart rate variability.
What Is Heart Rate Variability?
Normally, our heart beats at a regular rate. If you have a heart rate of 60 beats per minute (bpm), you’ll experience 60 beats in one minute, by definition.
However, the spacing between those heartbeats isn’t precisely one second. The competing forces of the sympathetic and parasympathetic nervous systems mediate the timing of every heartbeat we have.
There are variations in the timing between each heartbeat. By measuring this intra-beat difference, we can analyze a concept called heart rate variability.
When there’s more variation in the spacing between heartbeats, the phenomenon reflects signaling from the parasympathetic nervous system. Conversely, less variation in the spacing between heartbeats reflects a predominance of the sympathetic nervous system.
Analogous to the dashboard of the Tesla, by measuring HRV, we get an insight into our body’s current state.
Are we in a predominantly sympathetic situation (accelerating onto the freeway)? Or, are we in a parasympathetic situation (recharging our batteries and recovering)?
Why Measure HRV?
Heart rate variability first became popularized in the athletic community. As discussed in previous blog posts, physical training is a process of:
- Initiating stress in our body
- Recovering from that stress to come back stronger
- Coming to a new equilibrium of greater strength or aerobic capacity
Athletes trying to maximize their athletic performance want to know how much stress they can put their system under. How much recovery will they need? So, the HRV is uniquely suited to tell athletes whether they can tolerate more strain or need to recover.
For example, a weightlifter who just finished a big workout would need to check their HRV the next day. If the HRV went down, that would reflect a sympathetic predominance, meaning the body hadn’t recovered enough and they may need to modify their workout.
Conversely, if the weightlifter’s HRV were rising, it would indicate a parasympathetic predominance, meaning the body was successfully recovering and could tolerate a more intense workout.
The Role of Stress
In previous posts, we’ve explored the deleterious effects of excess stress. We’ve discussed how stress can cause stress belly and many other bad outcomes, including obesity, high blood pressure, diabetes, cancer, stroke, and heart attack.
The same gauge athletes use to determine whether they’re under stress or in stress recovery can also measure how much stress non-athletes are under.
Stress can be physiological, in terms of a tough workout, or psychological. Increased sympathetic tone and decreased HRV indicates higher stress levels.
We know how damaging stress can be, but it’s been challenging to quantify. Fortunately, we now have tools that accurately measure a body’s total burden of stress.
Enter: Garmin and other wearables that measure heart function.
How Does Garmin Measure Stress?
So, how does Garmin measure stress?
For the last 120 years, we’ve measured heart rate using electrical signals.
The first apparatus weighed over 600 lbs and required five people to operate. Today, a wearable heart rate monitor, like Garmin or an Apple Watch, connects to a smartphone app to detect and record data, including heart rate variability.
The newest development in iPhone watches and other wearables is an optic sensor mechanism that shines an LED light into the superficial skin. The sensor monitors the light reflected back to determine the pulse-by-pulse change in the shape of a tiny artery beneath the skin.
This technology has gotten remarkably accurate. As a result, we’re entering an era of readily-measurable HRV. Anyone who wears a Garmin, an Apple Watch, or another wearable that tracks heart function can potentially use it in this way.
As we explained above, HRV is an accurate way to quantify and measure stress.
Researchers have been studying HRV as it applies to various disease states. Just as stress is a risk factor for bad outcomes, so too is diminished heart rate variability. These outcomes include cardiovascular disease, cancer, diabetes, and inflammatory conditions.
How to Improve Your Heart Rate Variability
Wearables like Garmin and the Apple Watch could provide incredible new data for scientists to study and gain insights. By increasing sample sizes from a few participants in a laboratory to potentially hundreds of thousands of 24/7 users, the potential for vast amounts of data is staggering.
While we don’t have all the answers yet, we do know some basic ways you can improve your HRV (and your health in general).
- Get proper rest — ensure you get enough quality sleep.
- Reduce alcohol intake — studies show alcohol consumption diminishes your HRV.
- Maintain consistent eating and sleeping times — stay within your circadian rhythms.
- Meditate and practice deep breathing exercises — these can help with parasympathetic tone.
- Exercise — helps improve sympathetic tone.
What’s Next?
We began this post with the question, “How does Garmin measure stress?” We’ve answered that — Garmin and other wearables that measure heart function measure stress by detecting your heart rate variability (HRV).
We’ve also explained why measuring and monitoring your stress and HRV is important — both can affect your overall health and wellness.
You can take the first steps toward improving your HRV by following the tips listed above. If you want to further explore your heart rate variability and other important health indicators, that’s our specialty at Banner Peak Health.
We create personalized care plans for each of our members and focus on what’s important to you. Contact us today if you’re interested in our services.
Why ‘Outlive’ by Peter Attia Is One of the Best Books I’ve Ever Read
“Outlive: The Science and Art of Longevity” by Peter Attia is one of the best medical books I’ve ever read. I’m not alone in that assertion — Steven D. Levitt, New York Times bestselling author of “Freakonomics,” called it “One of the most important books you’ll ever read.”
“Outlive” is structured like most books in the self-help genre. Dr. Attia recounts his autobiographical journey, then entices the reader to follow him on the path he’s described.
His eclectic background informs his creative thought process and brings a different perspective to the medical challenges of prolonging life.
As a young man, Attia planned to become a professional boxer. Plans changed, and he earned undergraduate degrees in mathematics and engineering. From there, he studied medicine at Stanford and earned an M.D.
At the beginning of his career as a physician, he studied at Johns Hopkins Hospital in general surgery and at the National Institutes of Health as a surgical oncology fellow.
Today, he focuses on longevity and healthspan (the number of healthy, fully functioning years we have). What I appreciate most are the intellectual constructs he brings to the field.
He’s put a new spin on prevention, explaining that you’ll enhance your longevity by preventing things that cut your life short. A vital part of that is primary care internal medicine.
Why This Topic Strikes a Chord
In today’s post-pandemic society, we have an opportunity to shift the way we approach our health from defensive to offensive. Rather than merely reacting to a health issue, we can work proactively to prevent that health issue from happening in the first place. That appeals to many people, myself included.
The pandemic changed the world in many ways, but one potentially positive outcome is that people are much more cognizant of their health and wellness. That awareness means people realize the value of preventative methods.
Case in point: Dr. Attia’s book is a number one New York Times Best Seller and has nearly 3,000 5-star reviews on Amazon.
Dr. Attia’s Approach
Dr. Attia calls his approach Medicine 3.0 and refers to traditional medicine as Medicine 2.0. Here are the basic differences:
- Medicine 2.0 — physician waits for an illness to present, then runs tests, and diagnoses
- Medicine 3.0 — physician assesses risk for developing illness and works to prevent illness from ever occurring
The problem with Medicine 2.0 is the inherent limitations within the research. Traditionally, research takes decades of study and carefully controlled experimentation.
However, we can’t test humans the same way we test lab rats, especially when our goal is prevention rather than treatment. Who would commit to experimental lifestyle changes for decades for the sake of science?
Therefore, we can’t rely on the traditional methodology (clinically controlled trials) used by Medicine 2.0 to guide us in pursuing our goals in Medicine 3.0. We need to form a new body of scientific evidence using an alternative to randomized controlled studies.
Focus on Fundamentals
What I find most appealing about Dr. Attia’s approach to longevity is his focus on the fundamentals. The study of aging and longevity has yielded tremendous insights into the physiology of how our cells age.
Many people tout hypothetical pharmacological interventions as solutions to help us prolong our health and lifespan. However, I strongly agree with Dr. Attia that lifestyle modifications are the strongest and safest modalities.
He then introduces what he calls the Four Horsemen — the four leading causes of death and disability in Western society. They are:
The remainder of his book details therapeutic modalities, for which there is the best evidence for avoiding or staving off these Four Horsemen. The fundamentals he describes are what we’ve always referred to as lifestyle medicine.
He emphasizes:
Only then does Dr. Attia mention what he calls exogeneous molecules, or pharmacological treatments, which play a refreshingly small role in his extensive book.
The Banner Peak Health Connection
At Banner Peak Health, we always look for new diagnostic and therapeutic techniques to provide our patients with more personalized care. If you share that commitment, I highly recommend reading “Outlive” by Peter Attia, M.D. It’s quite a deep dive, but it’s well worth it.
What Dr. Attia brings to the practice of health at Banner Peak Health is a cognitive framework that validates much of what we’ve already been doing.
He also inspires new ways of thinking about the challenge of maintaining lifespan and healthspan as part of a longevity program. We plan to incorporate those insights into our practice.
Why Stress May Be Your Worst Enemy
Psychology becomes biology. When we think of emotions, we tend to think only of feelings and mental reactions. But as I’ve discussed before, the mind and the body are inextricably linked.
This linkage occurs via hormones, the substances produced by one cell that influence the biology of another. Hormones are how the body’s systems communicate.
For example, the adrenal glands produce adrenaline and cortisol in response to an accelerated heart rate, which can result from both biological stress and emotional stress. The selfsame hormones triggered by injury and lack of oxygen are also triggered by fear, worry, and anger.
Stress Is Here to Stay
Our stress response is adaptive. Our ancestors’ stress response (adrenaline release → increased heart rate → increased oxygen consumption → increased blood flow to muscles) helped them avoid predators in fight-or-flight scenarios. It’s how we as a species have persevered.
In modern society, stress is more chronic. It’s unlikely we’ll need to run from a tiger for a few short minutes (a temporary biological trigger), but we do spend the entire month worrying about paying our mortgage (a long-term emotional trigger).
We live in an epidemic of heart disease, cancer, and obesity. We can connect them all to the constant, dangerous levels of stress we endure daily. Unmanaged, this stress can trigger cascades of biological responses that result in detrimental outcomes.
5 Ways to Address Stress
Unfortunately, external sources of stress — illness or the loss of a loved one, for instance — are often beyond our control. In these cases, we need to understand and address our internal response to stress because it’s our only controllable factor.
Most of us are aware of our stress inbox — the external factors that generate our stress — but haven’t considered our stress outbox — our internal stress response. How do we process and mitigate stress?
Everyone is different, but these tools can be helpful for most people.
Exercise and Spend Time Outside
Exercise is a powerful means of stress reduction. Beyond that, you can also spend time in nature. Regardless of what you’re doing, simply being outside and seeing greenery helps relieve stress.
Prioritize Quality Sleep
We’ve previously discussed sleep and its importance for maintaining good health. Here, we’ll just underscore how poor sleep and chronic stress become a vicious cycle. Stress inhibits sleep, which compounds the stress response, which makes you prone to poor sleep, and so on.
It’s crucial to get sleep no matter what, but we realize this is easier said than done. Ask your doctor for help, and make sure your coping mechanisms don’t hinder quality sleep.
Embrace Social Connections
We humans are social creatures. We’ve survived as a species not just because of our own individual adaptations, but because of what we’ve done collectively.
Don’t ignore that evolutionary tendency. Seek religious and/or secular communities of like-minded people who will support and encourage you. “Going it alone” is not an appropriate stress response and will likely lead to increased stress levels.
Don’t Make It Worse
Avoid substances such as nicotine and alcohol. These potent chemicals make us more prone to stress and work against our ability to manage stress in a healthy way.
Seek Professional Help
You’re not alone in this struggle. Stress is a global epidemic affecting millions of people, and there are amazing therapists, counselors, and coaches available to help.
However, these professionals may have long waiting lists, or may not be available in your immediate area. If you lack the wherewithal to seek or secure professional help, consult your primary care physician.
The Banner Peak Health Difference
Here at Banner Peak Health, we’re thankful our patients see us as more than “just” their physical doctors. That’s certainly not how we see ourselves!
We recognize and appreciate the mind-body connection and regularly help our members with mental health concerns. If you need assistance pursuing a less stressful, more fulfilling life, we’re here to help.
How Often Should You Get Bloodwork Done?
How often should you get bloodwork done?
When it comes to bloodwork, many patients believe in a one-size-fits-all approach. Having labs ordered during their annual physical is enough, they think.
Well, not quite.
As much as we’d love a simple solution, health and medicine are seldom so straightforward. How often you should get bloodwork done, and which specific tests your physician orders, depends on your unique circumstances.
Most of us have heard of Elizabeth Holmes and her organization, Theranos. Holmes was a young, charismatic entrepreneur who promised to revolutionize medicine by introducing a personal device that would allow hundreds of tests to be run from a single finger prick.
In reality, the device never existed, and Elizabeth will spend the next 11 years in prison for fraud. The rest of us can watch a version of her story on Hulu.
I was an early skeptic of her theories — not the technology per se, but the fundamental premise that more testing in the hands of more people without medical supervision would make the world a healthier place.
Call me old-fashioned, but I believe the cognitive process of lab testing should intimately involve a healthcare provider. Medicine itself is a scientific endeavor, and at the core of all science is the scientific method: generate a hypothesis (a clinical question) and test it (gather data to try to answer your question).
For example, a diagnostic hypothesis of a fatigued person could generate lab tests to address the source of the fatigue. These might include blood count, hormone balance, etc., but all tests would align with the question we’re trying to answer — why is this person fatigued?
This is one of many strong arguments for why medical testing should always happen under the supervision of a trained professional — and why the question “How often should you get bloodwork done?” is answered, “It depends.”
Blood Test Categories
I like to separate diagnostic lab work into three categories. Defining and exploring these categories demonstrates the importance of medical supervision and how testing regimens can vary among individuals.
Category #1: Symptom-Generated
This category of bloodwork is symptom-directed, and physicians order it to answer a predefined clinical question — i.e. to determine the cause of a specific symptom, such as fatigue or chronic pain.
Someone who experiences right upper quadrant pain, for example, would get tests such as a liver function test.
Category #2: Screening Tests
Screening tests are more open-ended, but should still to an extent be guided by a hypothesis. Tests in this category are chosen based on a patient’s individual risk factors.
If a patient were overweight, we’d test their blood sugar levels to monitor their risk for diabetes. If a patient were on a drug like Protonix, they may be at risk for malabsorption of vitamins such as B12, so we’d want to check their B12 levels. As people age, their organs slowly lose function, so we test kidney function and blood count in older patients. Etc., etc.
Category #3: Disease Management
If a patient has an illness or chronic condition, they need more frequent lab testing to monitor their treatment.
The regularity of testing depends on the specific disease and treatment. For example, some illnesses, like thyroid disease, can be treated with hormone therapies, which need to be monitored frequently.
How Often Should You Get Bloodwork Done?
As I mentioned, it depends on the category and goal of the test.
Symptom-generated testing must happen as soon as symptoms occur. This type of testing isn’t required on a regular basis.
Screening tests are typically done annually because it’s convenient to tack them onto your annual physical. However, if your risk factors justify more frequent testing, consult your doctor to come up with an individualized testing schedule.
In my experience, testing for disease management usually occurs every 90 days (three months). It’s a common interval — A1C testing measures the average blood sugar over 90 days, finding equilibrium after adjusting thyroid medication usually takes 90 days, and adjusting to a new dosage of a cholesterol pill takes about three months.
Preparing for Labs
Many people think they need to fast before going for lab testing. That’s not the case at all. In fact, there are very few labs that necessitate fasting.
Only blood sugar (blood glucose) and cholesterol tests require fasting. However, technology has advanced enough that we can work around fasting for those tests — we understand some people can’t fast or have difficulty fasting.
In place of LDL cholesterol, we can order a more sophisticated test called an apolipoprotein B, which doesn’t require fasting. And for blood glucose, we can order the A1C, a non-fasting lab which looks at a person’s average blood sugar levels over the last 90 days.
Ultimately, labs don’t have to ruin your day — but they should still involve your doctor.
If you have additional questions about bloodwork, or any of our other preventative services here at Banner Peak Health, reach out. We’d love to speak with you.
Executive Physical: Is It Worth It?
Many people are drawn to concierge medicine for its attention to detail and to the individual.
For example, when people are due for their annual physical, they often want more than the traditional healthcare system can provide. This has led to the development of the “executive physical.”
Critiques of the Annual Physical
In 2015, The New England Journal of Medicine published a study claiming annual physicals were a waste of time and money, as they “do not reduce morbidity or mortality, and preventive care can be updated in other ways.”
The study caused an uproar in the medical community. Physicians all across America believed these researchers had insulted the foundations of the traditional healthcare experience.
That’s not exactly true. These researchers were really saying that it’s difficult to put a monetary value on the results of a typical primary care physical. They believed the healthcare establishment could better use its resources elsewhere.
The study holds some truth.
The traditional annual physical is constrained by time and insurance, and often, primary care physicians are unable to help their patients address all of their health care needs.
At Banner Peak Health, we’re free from those time and insurance constraints, meaning we can offer our patients more in the form of the executive physical.
But not all executive physicals are created equal.
The ‘Executive Physical’ Difference
Have you ever seen high-cotton paper? Elegant, high-end paper with cotton content to demonstrate its importance? I see it from time to time.
As the concept of the executive physical has gained popularity, many patients first turn to major academic medical institutions. However, that’s rarely their final stop. After leaving their medical institution of choice, these patients come to me with beautiful binders full of high-cotton paper printed with tons of data — that have never been opened.
To me, this demonstrates the potential weakness of an executive physical; it lacks the means to respond to all the detailed information it discovers.
Banner Peak Health strives to provide something more valuable.
Executive Physicals: The Banner Peak Health Difference
Our executive physical not only investigates possible risk factors, but also provides the structure to implement our findings.
If you’re busy enough to value the time spent on an executive physical, you’ll likely struggle to find enough time to implement the results. That’s how we differentiate ourselves — it comes down to time.
We don’t just generate. We implement.
That’s not to say larger academic institutions aren’t valuable — they have a lot of advanced equipment under one roof. But we take executive physicals a step further by customizing each exam according to the diagnostic studies appropriate for each individual.
We can dedicate the time necessary to provide the care you deserve, and we aren’t beholden to insurance when it comes to what applications, tests, and technologies we can use and order.
From Galleri testing to coronary artery calcium scores, we offer more comprehensive medical insights, and will help you implement solutions every step of the way. Without implementation, test results are just data points printed on expensive paper collecting dust on a shelf.
If you’re ready to implement, we’d love to welcome you as a member at Banner Peak Health. Contact us today.
The Two Types of Body Fat Worth Knowing About
Just as the adage “location, location, location” applies to real estate investing, the same applies to our fat cells.
All fat isn’t created equal. In fact, location highly determines the biology of our fat cells.
In this post, I’ll explain how two classic body types are related to two types of body fat, and why the differences between the two are worth noting.
Body Types and Types of Body Fat
The distribution of fat cells determines two classic human body types:
- The “apple” type — more fat cells located in the abdominal area, with smaller buttocks, hips, and thighs
- The “pear” type — more fat cells located in the buttocks, hips, and thighs, with a smaller midriff
The corresponding types of body fat are visceral fat and subcutaneous fat, respectively.
- Visceral fat = abdominal fat = fat in the gut = the apple body type
- Subcutaneous fat = fat in the thighs, hips, buttocks, and arms = the pear body type
Important Definitions
Let’s take a step back.
We all have a basic understanding that being overweight is “bad for you,” but what does that mean, exactly?
Defining ‘Overweight’
People tend to hyper-fixate on weight. We step on the scale, read the number, and, if it’s too high, we call weight the bad actor. But is it the weight that’s the problem?
There are more accurate ways to measure body composition, such as the body mass index (BMI), but we’ve discussed before why that can also be misleading. (BMI would have a linebacker signing up for Weight Watchers!) Better options, like the InBody scan, can establish an individual’s percentage of body fat and analyze visceral fat levels.
Still, though this information gets us closer, the real answer we’re looking for is the location of the weight and how that affects the metabolism.
Defining ‘Bad for You’
Data collected during the Women’s Health Initiative revealed that postmenopausal women (with normal BMIs) who had high fat cell distribution in the abdominal area (the apple body type) were three times more likely to have unfavorable health outcomes than women with fat cell distribution elsewhere (the pear body type) — even though none of the 2,700 women studied were overweight.
This study illustrates the difference in the biology of fat cells based on location.
Now we can talk precisely about what “being overweight” means and where it’s most dangerous to carry excess weight. There’s also extensive literature exploring the negative outcomes associated with excess visceral fat.
Types of Body Fat and Hormones
Each of us has billions of fat cells distributed all throughout our body, and each fat cell can release up to 20 different hormones. We can think of adipose tissue (fat) as an endocrine organ.
As we reviewed earlier, fat cells aren’t evenly distributed throughout the body. Age, gender, genetics, and hormones determine the location of our fat cells, and we can’t change any of those factors.
In general, the best way to discuss different types of body fat cells is in two main groups — visceral and subcutaneous — based on their location and function.
We’re always learning about our bodies; they’re incredibly complex. For example, in 1994, we discovered a hormone called leptin, which fat cells express to mediate hunger. Since then, we’ve discovered many other hormones secreted by fat cells that impact almost every aspect of our metabolism.
We can now answer the question “why is being overweight bad for you?” at the biological level. Adipocytes (fat cells) secrete hormonal signals called adipokines. The adipokine balance in our bodies determines our health.
Put simply, our fat cells, their location, and the hormones they produce are a huge determining factor in our overall health.
Our Priorities
As a physician, I want to use as many tools as possible to understand each patient’s risk of unfavorable health outcomes.
Understanding not just each person’s height and weight but also their fat distribution helps us to better understand their overall risk for illness, and subsequently, to mitigate that risk.
Today’s Takeaways
- There are essentially two types of body fat:
- Visceral (apple body type)
- Subcutaneous (pear body type)
- Excessive visceral body fat can drastically increase the risk of negative health outcomes, such as coronary artery disease and cancer.
- Fat cells aren’t evenly distributed throughout the body and play a major role in metabolism and overall health.
What Are the Health Benefits of Walking 10,000 Steps a Day?
The other evening, my wife and I were out walking our two dogs.
After a long day, I was ready to head in. My wife pulled out her phone and realized she hadn’t reached her daily goal of 10,000 steps. She asked if I could walk a few more blocks with her.
Although I was tired, I wanted to go with her. I knew it was good for my health, her health, and even the dogs’ health. But I was also curious about my wife’s fixation on the goal of 10,000 steps.
What are the health benefits of walking 10,000 steps a day? I decided to look into it.
Where Does the Idea of ‘10,000 Steps a Day’ Come From?
In 1965, a Japanese company called Yamasa Clock developed a new pedometer. They named it “Manpo-Kei,” which translates to “10,000 steps.”
Why? Because the Japanese character for the number 10,000 resembles a person walking.
That’s it. The name had nothing to do with medical science at all! Instead, it was a marketing decision that, over half a century later, is enshrined in a sort of folklore.
But the story doesn’t end there.
The Health Benefits of Walking 10,000 Steps a Day
We’re aware of the many benefits of aerobic exercise, from weight loss to mood elevation to a reduced risk of dementia.
Robust literature has assessed the dose-response curve for exercise — or, how much exercise yields optimal results.
According to a study published in 2019, which monitored 18,000 women over four years, 4,400 steps a day yields better results than 2,700 steps per day. And 7,500 steps per day is better still.
Another study published in 2020 looked at about 5,000 men and women over 10 years. Researchers found that by increasing steps per day from 4,000 to 8,000, subjects could reduce their risk of cardiovascular disease by 50%.
All these studies look for an association between walking and improved health outcomes. However, there’s the obvious confounder here: The more frail or sick you are, the less you walk. So there’s an unavoidable inaccuracy in these studies based on that confounding factor. Nonetheless, they’re being used to encourage people to walk more.
In 2022, results from the largest cohort study to date were released. In Britain, over 78,000 individuals with a mean age of 61 were followed for seven years. The study found that at 3,800 steps per day, dementia risk reduced by 25%, while at 9,800 steps per day, that risk reduced by up to 50%.
Another study looked at the same patient population for overall risk reduction in cancer mortality and cardiovascular death. Researchers found that the maximum benefit occurred at — get this — 10,000 steps per day.
The story has come full circle. After nearly 60 years, what began as a marketing gimmick has proven to be a healthy practice.
Today’s Takeaways
If exercise were a pill, it would be the safest, most powerful drug ever. Literature supports the notion that there are significant health benefits to walking 10,000 steps a day.
Don’t you hate it when your spouse is right?
Everyone knows exercise is good for you on an intellectual level. The challenge we face is helping people develop habits that encourage them to incorporate this behavior into their daily routine.
It’s helpful to find ways to exercise that are fun, or at the very least, less onerous. For example, walking with friends, family members, or furry family members may be enjoyable for you. And if tracking and counting steps helps motivate you to walk farther every day, go for it!
